The prognostic implications of night sweats in two cohorts of older patients.

BACKGROUND When asked, a significant number of patients report having experienced night sweats. Those who do are more likely to report decreased physical health, mental health, and quality of life. In most cases the cause of night sweats is unknown. We therefore do not know how much to worry about patients with this symptom. The present study examined associations between night sweats and mortality. METHODS We used logistic regression and proportional hazards analyses to investigate potential predictors of mortality, including night sweats reported at baseline, among 2 different cohorts of people older than 65 years of age (n = 682 and n = 852) who were followed for an average of 7.3 and 7.5 years, respectively. RESULTS Patients who reported night sweats were not more likely to die or to die sooner than those who did not report night sweats after controlling for age, sex, body mass index, education, and income. This held true as well for patients who reported more severe night sweats among the cohort in which the severity of night sweats was quantified. CONCLUSIONS Patients who report night sweats on a primary care health history questionnaire do not seem, on average, to be at increased risk for mortality.